KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMP3573 |
|---|---|
| Product Name | Human IL-6 Protein |
| Product Description | The Human IL-6 Protein(KMP3573) is produced in E. coli. The target gene encoding the mature form of human IL6 (NP_000591.1) (Val30-Met212) is expressed with an initial Met at the N-terminus. |
| Molecular Name | IL-6 |
| Alias | Human IL-6 Protein, IL-6 |
| Molecular Weight | 20.95 kDa |
| Species | Human |
| Size | 50ug, 100ug, 200ug |
| Host | E. coli |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <5.0 EU/mg determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Background | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
