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Catalog Number | KMP3978 |
---|---|
Product Name | Mouse Fas Ligand Protein, His Tag |
Product Description | The Mouse Fas Ligand Protein(KMP3978) is produced in Yeast. A DNA sequence encoding the Mouse Faslg (AAB02915.1) (Pro132-Leu279) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | Fas Ligand |
Alias | Fas Ligand Protein, Mouse Fas Ligand Protein, His Tag |
Size | 50ug, 100ug, 200ug |
Species | Mouse |
Host | Yeast |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Molecular Weight | 18.2 kDa |
Background | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |