KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMP4120 |
|---|---|
| Product Name | Mouse ALDH1A3 Protein, His Tag |
| Product Description | The Mouse ALDH1A3 Protein(KMP4120) is produced in E. coli. A DNA sequence encoding the Mouse ALDH1A3 (Q9JHW9) (Ala2-Pro512) is expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | ALDH1A3 |
| Alias | ALDH1A3 Protein, Mouse ALDH1A3 Protein, His Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Mouse |
| Host | E. coli |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | 50mM TRIS, 50mM NaCl pH8.0 |
| Purification | Affinity purification |
| Molecular Weight | 56.94 kDa |
| Background | Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
