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Recombinant Human ACE2 Protein, His Tag

Product Information
Catalog Number KMPH1835
Product Name Recombinant Human ACE2 Protein, His Tag
Alias Angiotensin-converting enzyme 2, ACE2
Size 100ug, 1mg
Species Human
Expression Host HEK293 Cells
Applications ELISA, WB
Source A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was expressed with a polyhistidine tag at the C-terminus.
Purity ≥95% as determined by SDS-PAGE.
SDS-PAGE Result
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Buffer Lyophilized from sterile PBS, pH 7.4.
Background Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.