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Catalog Number | KMPH1835 |
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Product Name | Recombinant Human ACE2 Protein, His Tag |
Alias | Angiotensin-converting enzyme 2, ACE2 |
Size | 100ug, 1mg |
Species | Human |
Expression Host | HEK293 Cells |
Applications | ELISA, WB |
Source | A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was expressed with a polyhistidine tag at the C-terminus. |
Purity | ≥95% as determined by SDS-PAGE. |
SDS-PAGE Result | ![]() |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Buffer | Lyophilized from sterile PBS, pH 7.4. |
Background | Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |