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Catalog Number | MA1506 |
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Product Name | Recombinant Human anti Mouse CD40 Ligand Monoclonal Antibody |
Alias | Anti-CD154 Antibody; Anti-CD40 Ligand Antibody; Anti-CD40L Antibody; Anti-gp39 Antibody; Anti-hCD40L Antibody; Anti-HIGM1 Antibody; Anti-IGM Antibody; Anti-IMD3 Antibody; Anti-T-BAM Antibody; Anti-TNFSF5 Antibody; Anti-TRAP Antibody |
Size | 100ul, 1ml |
Immunogen | Recombinant Human CD40L / CD154 / TNFSF5 protein |
Species | Mouse |
Host | Human |
Applications | ELISA |
Cross-Reactivity | Cross react with Human |
Buffer | 0.01M PBS, pH 7.4 |
Purification | Protein A |
Background | CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation. |
Storage | This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |