Service Line:+86-022-82164980
Address:FL-4, Building A5, International Enterprise Community, Tianjin, China
Email:[email protected]
Catalog Number | MA2626 |
---|---|
Product Name | Humanized Anti-HPV16/HPV31/HPV52/HPV58 mAb |
Product Description | The Humanized Anti-HPV16/HPV31/HPV52/HPV58 mAb (MA2626) is produced in CHO cells. This antibody can be used in ELISA and Neutralization test and is suitable for other immunoassay applications. |
Alias | Human Anti-HPV16/HPV31/HPV52/HPV58 mAb, Anti-HPV16 Monoclonal Antibody, Anti-HPV16 L1 Monoclonal antibody, HPV16 recombinant antibody, Human papillomavirus type 16 antibody, Anti-HPV31 Monoclonal Antibody, Anti-HPV31 L1 Monoclonal antibody, HPV31 recombinant antibody, Human papillomavirus type 31 antibody, Anti-HPV52 Monoclonal Antibody, Anti-HPV52 L1 Monoclonal antibody, HPV52 recombinant antibody, Anti-HPV58 L1 Monoclonal antibody, Anti-HPV Neutralizing Antibody |
Size | 100ug, 500ug, 1mg |
Species | HPV16/HPV31/HPV52/HPV58 |
Host | CHO |
Applications | ELISA, Neutralization |
Purity | > 90% as determined by SEC-HPLC |
Cross-reactivity | Cross reacts with HPV16, HPV31, HPV52 and HPV58. |
Biological Activity | The neutralization activity is measured by microneutralization assay in vitro. The infection was neutralized by increasing concentrations of Anti-HPV Neutralizing Antibody. IC50(HPV16) is 0.07 ng/mL. IC50(HPV31) is 0.12 ng/mL. IC50(HPV52) is 2.07ng/mL. IC50(HPV58) is 0.13ng/mL. |
Buffer | PBS, pH7.4 |
Purification | Affinity chromatography and cation exchange chromatography |
Background | HPV is a double-stranded circular DNA virus. HPV infection is the most prevalent sexually transmitted disease, which results in over 14000000 individuals annually and 80% of sexually active individuals in their lifetime to be infected from HPV. As of September 2023, 231 HPV types have been identified. Different types of human neoplasia (HPV) cause different types of disease. The two HPV types, HPV16 and HPV18, have been identified as the most prevalent types associated with cervical cancer and are accountable for 70% of cervical cancers and precancerous cervical lesions. The human papillomavirus 9-valent recombinant vaccine has VLPs for two low-risk HPV6 and seven high-risk HPV11, HPV16, HPV18, HPV31, HPV33, HPV45, HPV52, and HPV58. This vaccine can prevent 90% of cervical cancers and 90% of genital warts. |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Shipping Condition | Shipped on ice packs. |
Clonity | Monoclonal |
Note | This product is for research use only. |