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Humanized Anti-HPV16/HPV31/HPV52/HPV58 mAb

Product Information
Catalog Number MA2626
Product Name Humanized Anti-HPV16/HPV31/HPV52/HPV58 mAb
Product Description The Humanized Anti-HPV16/HPV31/HPV52/HPV58 mAb (MA2626) is produced in CHO cells. This antibody can be used in ELISA and Neutralization test and is suitable for other immunoassay applications.
Alias Human Anti-HPV16/HPV31/HPV52/HPV58 mAb, Anti-HPV16 Monoclonal Antibody, Anti-HPV16 L1 Monoclonal antibody, HPV16 recombinant antibody, Human papillomavirus type 16 antibody, Anti-HPV31 Monoclonal Antibody, Anti-HPV31 L1 Monoclonal antibody, HPV31 recombinant antibody, Human papillomavirus type 31 antibody, Anti-HPV52 Monoclonal Antibody, Anti-HPV52 L1 Monoclonal antibody, HPV52 recombinant antibody, Anti-HPV58 L1 Monoclonal antibody, Anti-HPV Neutralizing Antibody
Size 100ug, 500ug, 1mg
Species HPV16/HPV31/HPV52/HPV58
Host CHO
Applications ELISA, Neutralization
Purity > 90% as determined by SEC-HPLC
Cross-reactivity Cross reacts with HPV16, HPV31, HPV52 and HPV58.
Biological Activity The neutralization activity is measured by microneutralization assay in vitro. The infection was neutralized by increasing concentrations of Anti-HPV Neutralizing Antibody. IC50(HPV16) is 0.07 ng/mL. IC50(HPV31) is 0.12 ng/mL. IC50(HPV52) is 2.07ng/mL. IC50(HPV58) is 0.13ng/mL.
Buffer PBS, pH7.4
Purification Affinity chromatography and cation exchange chromatography
Background HPV is a double-stranded circular DNA virus. HPV infection is the most prevalent sexually transmitted disease, which results in over 14000000 individuals annually and 80% of sexually active individuals in their lifetime to be infected from HPV. As of September 2023, 231 HPV types have been identified. Different types of human neoplasia (HPV) cause different types of disease. The two HPV types, HPV16 and HPV18, have been identified as the most prevalent types associated with cervical cancer and are accountable for 70% of cervical cancers and precancerous cervical lesions. The human papillomavirus 9-valent recombinant vaccine has VLPs for two low-risk HPV6 and seven high-risk HPV11, HPV16, HPV18, HPV31, HPV33, HPV45, HPV52, and HPV58. This vaccine can prevent 90% of cervical cancers and 90% of genital warts.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Shipping Condition Shipped on ice packs.
Clonity Monoclonal
Note This product is for research use only.