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Catalog Number | MOP2081 |
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Product Name | Recombinant Mouse Btn1a1/Butyrophilin Protein, His Tag |
Product Description | Recombinant Mouse Btn1a1/Butyrophilin Protein, His Tag (MOP2081) contains the mouse Btn1a1(Ala27-Trp247) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | Btn1a1 |
Uniprot ID | Q62556 |
Alias | Btn, butyrophilin, subfamily 1, member A1 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Mouse |
Host | Mammalian cells |
Molecular Weight | 24.31 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |