KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | MOP2116 |
|---|---|
| Product Name | Recombinant Mouse Ctnnb1 Protein, His Tag |
| Product Description | Recombinant Mouse Ctnnb1 Protein, His Tag (MOP2116) contains the mouse Ctnnb1(Met1-Leu781) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | Ctnnb1 |
| Uniprot ID | Q02248 |
| Alias | Bfc, Mesc, Catnb, catenin(cadherin associated protein), beta 1 |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Mouse |
| Host | Mammalian cells |
| Molecular Weight | 87.34 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | β-catenins are cytoplasmic proteins that are ubiquitously expressed. These proteins associate with E-cadherin at cellular junctions. β-catenin interacts with TCF and LEF transcription factors and is an essential member of the Wingless-Wnt signal transduction pathway. The adenomatous polyposis coli (APC) tumor-suppressor protein, together with Axin and GSK3β, form a Wnt-regulated signaling complex that mediates phosphorylation-dependent degradation of β-catenin by the proteasome. APC and Siah-1 mediate a novel β-catenin degradation pathway linking p53 activation to cell cycle control. Activating mutations in the human β-catenin gene have been found in human colon cancer and melanomas. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
