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Rabbit Anti Human BNP Polyclonal Antibody

Product Information
Catalog Number PA12838
Product Name Rabbit Anti Human BNP Polyclonal Antibody
Product Description The Rabbit Anti Human BNP Polyclonal Antibody was obtained by affinity purification from a rabbit immunized with a purified synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
Clonity Polyclonal
Alias BNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP
Size 50ul, 100ul, 200ul
Species Human
Host Rabbit
Applications ELISA, WB, IHC-P, IF/ICC
Immunogen A synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1)
Cross-reactivity Human, Mouse, Rat
Buffer Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Purification Affinity Purification
Background This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Storage Store at -20℃. Avoid freeze / thaw cycles.