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Catalog Number | PA12838 |
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Product Name | Rabbit Anti Human BNP Polyclonal Antibody |
Product Description | The Rabbit Anti Human BNP Polyclonal Antibody was obtained by affinity purification from a rabbit immunized with a purified synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1) |
Clonity | Polyclonal |
Alias | BNP antibody, BNP polyclonal antibody, BNP Rabbit pAb, BNP, Iso-ANP |
Size | 50ul, 100ul, 200ul |
Species | Human |
Host | Rabbit |
Applications | ELISA, WB, IHC-P, IF/ICC |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP (NP_002512.1) |
Cross-reactivity | Human, Mouse, Rat |
Buffer | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
Purification | Affinity Purification |
Background | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |