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Mouse Anti-Sabin Poliovirus Type III MAb

Product Information
Catalog Number PA2003
Product Name Mouse Anti-Sabin Poliovirus Type III MAb
Clonity Monoclonal
Size 100ug, 500ug
Host Species Mouse
Purification Protein A/G
Buffer 0.1M PBS, PH 8.0
Immunogen Inactivated Sabin Poliovirus Type III
Appllications ELISA, WB
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Background Poliovirus infects human cells by binding to an immunoglobulin-like receptor, CD155, (also known as the poliovirus receptor (PVR)) on the cell surface. Interaction of poliovirus and CD155 facilitates an irreversible conformational change of the viral particle necessary for viral entry.Attached to the host cell membrane, entry of the viral nucleic acid was thought to occur one of two ways: via the formation of a pore in the plasma membrane through which the RNA is then “injected” into the host cell cytoplasm, or that the virus is taken up by receptor-mediated endocytosis.
Storage Store at 4°C for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition Shipped on ice packs.