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Catalog Number | YR1301 |
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Product Name | Anti-Human ACVR2A & ACVR2B Recombinant Antibody |
Molecular Name | Bimagrumab |
Alias | Anti-ACVR2A & ACVR2B Recombinant Antibody, Research Grade Bimagrumab |
CAS Number | 1356922-05-8 |
Target | ACVR2A & ACVR2B[Homo sapiens] |
Isotype | IgG1 Lambda |
Clonity | Monoclonal |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | FCM, IP, ELISA, Neut, FuncS, IF, ICC, MRI |
Buffer | PBS, pH7.5 |
Background | Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |