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Anti-Human ACVR2A & ACVR2B Recombinant Antibody

Product Information
Catalog Number YR1301
Product Name Anti-Human ACVR2A & ACVR2B Recombinant Antibody
Molecular Name Bimagrumab
Alias Anti-ACVR2A & ACVR2B Recombinant Antibody, Research Grade Bimagrumab
CAS Number 1356922-05-8
Target ACVR2A & ACVR2B[Homo sapiens]
Isotype IgG1 Lambda
Clonity Monoclonal
Source CHO Cells
Size 1mg, 5mg
Concentration 1mg/ml
Purity >95% as determined by SDS-PAGE
Applications FCM, IP, ELISA, Neut, FuncS, IF, ICC, MRI
Buffer PBS, pH7.5
Background Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration.
Storage It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.