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Catalog Number | YR1386 |
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Product Name | Anti-Human DLL3 Recombinant Antibody |
Molecular Name | Rovalpituzumab |
Alias | Anti-DLL3 Recombinant Antibody, Research Grade Rovalpituzumab |
CAS Number | 1613313-01-1 |
Target | DLL3[Homo sapiens] |
Isotype | IgG1 Kappa |
Clonity | Monoclonal |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Buffer | PBS, pH7.5 |
Background | Rovalpituzumab tesirine (Rova-T) is an experimental antibody-drug conjugate targeting the protein DLL3 on tumor cells. It was originally developed by Stemcentrx and was purchased by AbbVie. It was tested for use in small-cell lung cancer, but development was terminated after unsuccessful phase III trial. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |