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CD70 Target

CD70 was discovered in the early 1990s as a ligand for CD27, a member of the TNF receptor superfamily. CD27 is predominantly expressed in various immune cells, including T cells, B cells, and natural killer (NK) cells. In contrast, CD70 is expressed on antigen-presenting cells (APCs) such as dendritic cells and activated B cells. The interaction between CD27 and CD70 is essential for an appropriate immune response. CD70 is a costimulatory molecule that interacts with the receptor CD27 on T cells. This interaction provides crucial signals for T cell activation, proliferation and differentiation. It enhances antigen-specific immune responses, especially within T-cell-mediated immunity. CD70-CD27 interactions also play a role in B cell activation. They support B cell proliferation, differentiation into plasma cells and antibody production. This interaction contributes to the development of an effective humoral immune response. CD70 is involved in generating memory T cells, which are essential for long-term immunity. The signaling mediated by CD70 during T cell that exhibit heightened responsiveness upon re-exposed to the same antigen.

 

KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality CD70 target proteins, CD70 target antibodies and other high-quality target products for research institutions, universities and comapanies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality CD70 target-related products and promoting the continuous innovation and development in the field of biotechnology.

 

The featured target CD70 protein products launched by KMD Bioscience:

 

CAT#

Product Name

Species

Host

Size

Inquiry

MOP1865

Mouse CD70/CD27L Protein, Fc Tag

Mouse

HEK293 Cells

50ug, 200ug

Inquiry

KMH237

Recombinant Human CD70 Protein, Fc Tag

Human

Mammalian cells

50ug, 100ug

Inquiry

KMP2733

Human CD70 Protein, hFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2734

Human CD70 Protein, mFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2735

Human CD70 Protein, rFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2736

Human CD70 Protein, hFc Tag, Avi Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2255

Human CD70 Protein, mFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2377

Human CD70 Protein, Fc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP4014

Mouse CD70 Protein, His Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP4015

Mouse CD70 Protein, His Tag, Avi Tag

Mouse

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP4207

Rat CD70 Protein, His Tag

Rat

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

 

The featured target CD70 protein products launched by KMD Bioscience:

 

CAT#

Product Name

Species

Host

Appliance

Size

Inquiry

PA10403

Rabbit Anti-Human CD70 pAb

Human

Rabbit

IF

50ul, 100ul

Inquiry

PA10497

Rabbit Anti-Human CD70 pAb

Human

Rabbit

IF

50ul, 100ul

Inquiry

PA12696

Rabbit Anti-Human CD70 pAb

Human

Rabbit

WB, IHC, IF

50ul, 100ul

Inquiry

 

Other advantageous products from KMD Bioscience: