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CD3E Target

The CD3E gene (Gene ID:916) is a component of the CD3 complex, which consists of CD3E, CD3D and CD3Z (also known as CD3-γ, δ and ζ, respectively). These proteins are associated with the TCR and are essential for the function of T cell . In particular, CD3E acts as the ε-chain within the CD3 complex. CD3E is involved in the development of T cells by being expressed early in T cell precursors and facilitating assembly and surface expression of the TCR complex. Without functional CD3E, normal T cell development is impaired. Furthermore, it is essential for antigen recognition by forming a complex with CD3D and CD3Z to complete the overall structure of the TCR complex. This complex binds to antigenic peptides presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E serves as a target for immunotherapy, particularly in the development of bispecific antibodies (BsAbs) and chimeric antigen receptor (CAR) T-cell therapies. BsAbs conjugated with CD3E and tumor-specific antigens redirect T cells to attack cancer cells, while CAR T cells modified with CD3E-specific receptors exhibit promise for a wide range of applications in cancer therapy.

 

KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality CD3E proteins, CD3E antibodies and other high-quality target products to research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality CD3E related products and promoting the continuous innovation and development in the field of biotechnology.

 

The featured target CD3E protein products launched by KMD Bioscience:

 

CAT#

Products Name

Specise

Host

Size

Inquiry

KMPH2475

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH2476

Human CD3E Protein, His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

PM193

Rhesus CD3E Protein, Fc Tag

Rhesus

HEK293 Cells

20ug, 50ug

Inquiry

PM194

Rhesus CD3E Protein, His Tag

Rhesus

HEK293 Cells

20ug, 50ug

Inquiry

MOP1967

Mouse CD3D & CD3E Protein

Mouse

HEK293 Cells

 

Inquiry

KMPH5772

Human CD3D & CD3E Protein

Human

HEK293 Cells

 

Inquiry

MOP1968

Mouse CD3D & CD3E Protein

Mouse

HEK293 Cells

 

Inquiry

KMPH5777

Human CD3D & CD3E Protein

Human

HEK293 Cells

 

Inquiry

KMPH5780

Human CD3E & CD3G Protein, His & Fc Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

MOP1971

Mouse CD3E & CD3G Protein, Fc Tag

Mouse

HEK293 Cells

20ug, 100ug

Inquiry

PM142

Cynomolgus Monkey CD3D & CD3E Protein

Cynomolgus Monkey

 

 

Inquiry

KMPH6059

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH6065

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH6187

Human CD3E Protein, Strep Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH6231

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH6239

Human CD3D & CD3E Protein

Human

 

 

Inquiry

KMPH6241

Human CD3E Protein, Fc Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMPH6261

Human CD3D & CD3E Protein

Human

 

 

Inquiry

KMPH6278

Human CD3D & CD3E Protein

Human

 

 

Inquiry

KMPH6282

Human CD3E Protein, Fc & His Tag

Human

HEK293 Cells

20ug, 50ug

Inquiry

KMH152

Recombinant Human CD3E Protein, His Tag

Human

Mammalian cells

50ug, 100ug

Inquiry

KMP2811

Human CD3e Protein, hFc Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

KMP2812

Human CD3e Protein, His Tag

Human

CHO Cells

50ug, 100ug, 200ug

Inquiry

KMP3539

Human CD3D & CD3E Heterodimer Protein, His Tag

Human

HEK293 Cells

50ug, 100ug, 200ug

Inquiry

 

The featured target CD3E antibody products launched by KMD Bioscience:

 

CAT#

Products Name

Specise

Host

Appliance

Size

Inquiry

PA6053

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC

50ul, 100ul

Inquiry

PA6055

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC, IF

50ul, 100ul

Inquiry

PA9777

Rabbit Anti-Human CD3EAP pAb

Human

Rabbit

WB

50ul, 100ul

Inquiry

PA11011

Rabbit Anti-Human CD3E pAb

Human

Rabbit

WB, IHC, IP

50ul, 100ul

Inquiry

MA500

Rabbit Anti-Human CD3E mAb

Human

Rabbit

WB, IHC

50ul, 100ul

Inquiry

MA736

Rabbit Anti-Human CD3(epsilon+gamma)/CD3E+CD3G mAb

Human

Rabbit

WB, ELISA, FC

50ul, 100ul

Inquiry

 

Other advantageous products from KMD Bioscience: