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Catalog Number | KMH1238 |
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Product Name | Recombinant Human ICOS Protein, Fc Tag |
Product Description | Recombinant Human ICOS Protein, Fc Tag (KMH1238) contains the human ICOS(Glu21-Phe141) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
Molecular Name | ICOS |
Uniprot ID | Q9Y6W8 |
Alias | AILIM, CD278, CVID1, inducible T cell costimulator |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 38.31 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |