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Recombinant Human CD278/ICOS Protein, Fc Tag

Product Information
Catalog Number KMH427
Product Name Recombinant Human CD278/ICOS Protein, Fc Tag
Product Description Recombinant Human CD278/ICOS Protein, Fc Tag (KMH427) contains the human ICOS(Met1-Lys140) was fused with the C-terminal Fc Tag and expressed in Mammalian cells.
Molecular Name ICOS
Uniprot ID Q9Y6W8
Alias AILIM, CD278, CVID1, inducible T cell costimulator
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 39.99 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS, pH7.5
Purification Affinity Purification
Background Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.