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Catalog Number | KMH1340 |
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Product Name | Recombinant Human LIGHT/TNFSF14 Protein, His Tag |
Product Description | Recombinant Human LIGHT/TNFSF14 Protein, His Tag (KMH1340) contains the human TNFSF14(Leu83-Val240) was fused with the N-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | TNFSF14 |
Uniprot ID | O43557 |
Alias | LTg, CD258, HVEML, LIGHT, TNF superfamily member 14 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 17.38 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | LIGHT is a type II transmemebrane protein and a member of the TNF cytokine family also referred to as TNFSF14 and it is identical with HVEM ligand. LIGHT is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3). |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |