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Recombinant Human CD258/TNFSF14 Protein, His Tag

Product Information
Catalog Number KMH409
Product Name Recombinant Human CD258/TNFSF14 Protein, His Tag
Product Description Recombinant Human CD258/TNFSF14 Protein, His Tag (KMH409) contains the human TNFSF14(Leu59- Val240) was fused with the N-terminal His Tag and expressed in Mammalian cells.
Molecular Name TNFSF14
Uniprot ID O43557
Alias LTg, CD258, HVEML, LIGHT, TNF superfamily member 14
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 20.02 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background LIGHT is a type II transmemebrane protein and a member of the TNF cytokine family also referred to as TNFSF14 and it is identical with HVEM ligand. LIGHT is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.