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Recombinant Human CD40 Protein, His Tag

Product Information
Catalog Number KMH195
Product Name Recombinant Human CD40 Protein, His Tag
Product Description Recombinant Human CD40 Protein, His Tag (KMH195) contains the human CD40(Met1-Arg193) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name CD40
Uniprot ID P25942
Alias p50, Bp50, CDW40, TNFRSF5, CD40 molecule
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 22.32 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS, pH7.5
Purification Affinity Purification
Background CD4 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD4L) on TH cells to CD4 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.