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Catalog Number | KMH195 |
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Product Name | Recombinant Human CD40 Protein, His Tag |
Product Description | Recombinant Human CD40 Protein, His Tag (KMH195) contains the human CD40(Met1-Arg193) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | CD40 |
Uniprot ID | P25942 |
Alias | p50, Bp50, CDW40, TNFRSF5, CD40 molecule |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 22.32 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS, pH7.5 |
Purification | Affinity Purification |
Background | CD4 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD4L) on TH cells to CD4 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |