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Recombinant Human CD271/NGFR Protein, His Tag

Product Information
Catalog Number KMH420
Product Name Recombinant Human CD271/NGFR Protein, His Tag
Product Description Recombinant Human CD271/NGFR Protein, His Tag (KMH420) contains the human NGFR(Met1-Asn250) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name NGFR
Uniprot ID P08138
Alias CD271, p75NTR, TNFRSF16, p75(NTR), Gp80 LNGFR, p75 ICD, nerve growth factor receptor
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 27.5 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation. It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.