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Catalog Number | MOP2229 |
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Product Name | Recombinant Mouse NGF R/TNFRSF16 Protein, Fc Tag |
Product Description | Recombinant Mouse NGF R/TNFRSF16 Protein, Fc Tag (MOP2229) contains the mouse Ngfr(Gly20-Asn243) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
Molecular Name | Ngfr |
Uniprot ID | Q9Z0W1 |
Alias | p75, LNGFR, p75NTR, RNNGFRR, Tnfrsf16, nerve growth factor receptor |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Mouse |
Host | Mammalian cells |
Molecular Weight | 49.64 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation. It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |