Recombinant Human CD357/TNFRSF18 Protein, His Tag

Product Information

Catalog Number	KMH489
Product Name	Recombinant Human CD357/TNFRSF18 Protein, His Tag
Product Description	Recombinant Human CD357/TNFRSF18 Protein, His Tag (KMH489) contains the human TNFRSF18(Met1-Glu161) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name	TNFRSF18
Uniprot ID	Q9Y5U5
Alias	AITR, GITR, CD357, GITR D, ENERGEN, TNF receptor superfamily member 18
Protein Family	CD molecule
Size	50ug, 100ug
Species	Human
Host	Mammalian cells
Molecular Weight	17.71 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as TNFRSF18, is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.1 GITR is involved in the regulation of T-cell receptor mediated cell death. Constitutive expression of a transfected GITR gene induces resistance to apoptosis induced by anti CD3 monoclonal antibodies. GITR ligand interferes with the suppressor activity of CD4(+) CD25(+) regulatory T-cells.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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