Recombinant Human GITRL/TNFSF18 Protein, His Tag

Product Information

Catalog Number	KMH519
Product Name	Recombinant Human GITRL/TNFSF18 Protein, His Tag
Product Description	Recombinant Human GITRL/TNFSF18 Protein, His Tag (KMH519) contains the human TNFSF18(Glu74-Ser199) was fused with the N-terminal His Tag and expressed in Baculovirus-Insect cells
Molecular Name	TNFSF18
Uniprot ID	Q9UNG2
Alias	TL6, AITRL, GITRL, TNLG2A, hGITRL, TNF superfamily member 18
Protein Family	Immune checkpoint
Size	50ug, 100ug
Species	Human
Host	Baculovirus-Insect cells
Molecular Weight	13.97 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	Please contact our customer service for more information.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	Osteostat is the cytokine that binds to TNFRSF18/AITR/GITR and is important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. Osteostat is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells after stimulation by lipopolysaccharides. Osteostat protein is detectable in human microvascular EC and is highly up-regulated by IFN-alpha and IFN-beta. Osteostat inhibit differentiation of osteoclasts from monocytic precursor cells.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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