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Catalog Number | KMH519 |
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Product Name | Recombinant Human GITRL/TNFSF18 Protein, His Tag |
Product Description | Recombinant Human GITRL/TNFSF18 Protein, His Tag (KMH519) contains the human TNFSF18(Glu74-Ser199) was fused with the N-terminal His Tag and expressed in Baculovirus-Insect cells |
Molecular Name | TNFSF18 |
Uniprot ID | Q9UNG2 |
Alias | TL6, AITRL, GITRL, TNLG2A, hGITRL, TNF superfamily member 18 |
Protein Family | Immune checkpoint |
Size | 50ug, 100ug |
Species | Human |
Host | Baculovirus-Insect cells |
Molecular Weight | 13.97 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Osteostat is the cytokine that binds to TNFRSF18/AITR/GITR and is important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. Osteostat is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells after stimulation by lipopolysaccharides. Osteostat protein is detectable in human microvascular EC and is highly up-regulated by IFN-alpha and IFN-beta. Osteostat inhibit differentiation of osteoclasts from monocytic precursor cells. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |