Cynomolgus TNFSF18 Protein, His Tag

Product Information

Catalog Number	KMP2266
Product Name	Cynomolgus TNFSF18 Protein, His Tag
Product Description	The Cynomolgus TNFSF18 Protein(KMP2266) is produced in HEK293 Cells and the target gene encoding Glu74-Ser199 is expressed with a 6His tag at the C-terminus.
Molecular Weight	14.52 kDa
Alias	Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor ligand superfamily member 18, TNFSF18
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purification	Affinity purification
Purity	>95% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Uniprot	A0A2K5UCD9
SDS-PAGE
Background	TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation of NF-kappa-B. As Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. It also regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Applications	Size	Price
PAV4079	Rabbit Anti-TNF18/TNFSF18 Polyclonal Antibody	Human	Rabbit	WB, ELISA	100ul	Inquiry
KMH519	Recombinant Human GITRL/TNFSF18 Protein, His Tag	Human	Baculovirus-Insect cells		50ug, 100ug	Inquiry
PA15340	Rabbit Anti-Human TNFSF18 pAb	Human	Rabbit		50μl, 100μl	Inquiry