KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMH897 |
|---|---|
| Product Name | Recombinant Human CNTF Protein, No Tag |
| Product Description | Recombinant Human CNTF Protein, No Tag (KMH897) contains the human CNTF(Ala2-Met200) was fused without Tag and expressed in E. coli. |
| Molecular Name | CNTF |
| Uniprot ID | P26441 |
| Alias | CNTF, ciliary neurotrophic factor |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Human |
| Host | E. coli |
| Molecular Weight | 22 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | Please contact our customer service for more information. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor. CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
