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Catalog Number | KMP2305 |
---|---|
Product Name | Human CD47 Protein, Fc Tag, Avi Tag |
Product Description | The Human CD47 Protein(KMP2305) is produced in HEK293 Cells and the target gene encoding Gln19-Pro139 is expressed with a Fc, Avi tag at the C-terminus. |
Molecular Weight | 13.73 kDa |
Alias | Leukocyte Surface Antigen CD47, MER6 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purification | Affinity purification |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | 20mM PB, 150mM NaCl, pH7.4 |
Uniprot | A0A0A1TSG4#structure |
Background | CD47(Integrin-Associated Protein,IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |