KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMP4199 |
|---|---|
| Product Name | Rat TFRC Protein, His Tag |
| Product Description | The Rat TFRC Protein(KMP4199) is produced in HEK293 Cells. A DNA sequence encoding the Rat TFRC (Q99376) (Gly87-Phe761) is expressed, with a polyhistidine tag at the N-terminus. |
| Molecular Name | TFRC |
| Alias | TFRC Protein, Rat TFRC Protein, His Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Rat |
| Host | HEK293 Cells |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | 20mM Tris, 150mM NaCl, 0.02% Tween80, 5% Mannitol, pH7.5 |
| Purification | Affinity purification |
| Molecular Weight | 78.59 kDa |
| Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC/CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC/CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC/CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
