KMD Bioscience Co., Ltd.
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Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMP4205 |
|---|---|
| Product Name | Rat TNFSF12 Protein, hFc Tag |
| Product Description | The Rat TNFSF12 Protein(KMP4205) is produced in HEK293 Cells. A DNA sequence encoding the rat TNFSF12 (NP_001001513.2)(Arg105-His249) is expressed with Fc region of human IgG1 at the N-terminus. |
| Molecular Name | TNFSF12 |
| Alias | TNFSF12 Protein, Rat TNFSF12 Protein, hFc Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Rat |
| Host | HEK293 Cells |
| Purity | >85% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Molecular Weight | 44.4 kDa |
| Background | TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
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