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Catalog Number | KMH152 |
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Product Name | Recombinant Human CD3E Protein, His Tag |
Product Description | Recombinant Human CD3E Protein, His Tag (KMH152) contains the human CD3E(Met1-Asp126) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | CD3E |
Uniprot ID | P07766 |
Alias | T3E, TCRE, IMD18, CD3e molecule |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 12.69 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS, pH7.5 |
Purification | Affinity Purification |
Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |