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Antibody Application Platform

KMD Bioscience has an established R&D team at the cutting edge of technology to provide you with comprehensive antibody downstream engineering services, including antibody purification, antibody pairing (ELISA Kits development), antibody sequencing and antibody labeling services, etc.

We assist scientists worldwide in providing upstream and downstream services for antibody discovery. We produce antibodies in several ways, including phage display technology, hybridoma technology, single B cell sorting technology, recombinant antibody production technology, etc. We can produce traditional antibodies such as monoclonal antibodies and polyclonal antibodies, as well as antibody fragments such as nanobodies, Fab antibodies, and scFv antibodies, helping scientists worldwide accelerate the process of drug discovery.

 

Our Antibody Application Related Services

 

 

Antibody Labeling Service

 

Immunological testing usually involves the modification of antibodies. Our scientists can provide high-quality antibody labeling services, including fluorescent molecular markers (FITC, FAM, etc.), vector coupling (agarose beads, magnetic bead coupling, etc. ) and enzyme labeling (HRP, AP, etc.) and biotin labeling, etc.

Our antibody labeling services include: AP (alkaline phosphatase) labeling, horseradish peroxidase (HRP) labeling, β - galactosidase labeling, biotin labeling, glucose oxidase labeling, antibody fluorescent dye labeling, etc. to help you solve antibody labeling related research topics.

 

 

Figure 1 Types of antibody markers

 

Antibody Sequencing Service

 

Using the advanced Orbitrap Fusion Lumos mass spectrometer and powerful antibody sequencing data processing software, combined with gene sequencing and bioinformatics database, KMD Bioscience has established a new generation of antibody sequencing platform to achieve rapid and accurate analysis of the primary structure of antibodies, thus ensuring the accuracy of each antibody sequencing. Antibody sequencing services for various species are available. We also provide hybridoma sequencing services.

 

Antibody Purification Service

 

Protein purification is the process of separating and purifying proteins from mixtures (such as cell extracts, tissue culture media, etc.), separating the desired proteins from other impurities (such as non target proteins, nucleic acids, lipids, small molecules, cell debris, etc.), and obtaining high-purity protein. KMD Bioscience provide protein A/G affinity purification, ligand affinity purification, and affinity chromatography purification.

 

Antibody Pairing Service

 

Antibody pairing is critical for the development of ELISA kits. We have an experienced scientific team for antibodies to develop clinical assays and to provide you with comprehensive enzyme-linked immunoassay kit development services, including detection sensitivity verification, linear range verification, repeatability verification, specificity verification and thermal stability (37°C or 25°C thermal stability) verification. KMD Bioscience has successfully developed a small molecule detection kit with a detection sensitivity of 0.1 ppb.

 

 

Figure 2 ELISA determination principle

 

Small Molecule Antigen Development

 

KMD Bioscience provide hapten and antigen production and modification services. Small molecules or haptens do not have immunogenicity, but can induce antibody reactions when bound to carrier proteins. Then, the hapten reacts specifically with the antibodies produced against it, resulting in immune or allergic reactions. Therefore, although the hapten itself cannot trigger an antibody reaction, it can bind to the carrier and act as an antigen. You only need to provide the ideas or sequences you want to explore, and our team will help you create a fully customized and complete experimental plan. After years of practice, KMD Bioscience has accumulated rich experience in small molecule coupling design and antibody production. We offer customized services or derivative synthesis services to meet your personalized needs, providing haptens with different tethers or complete antigens with different carrier proteins.

 

How to Order?

 

If you have any questions regarding our services or products, please feel free to contact us by E-mail: [email protected] or Tel: +86-400-621-6806