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Catalog Number | KMP4281 |
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Product Name | Rat Flt3 Ligand Protein, His Tag |
Product Description | The Rat Flt3 Ligand Protein(KMP4281) is produced in Insect Cells. A DNA sequence encoding the rat FLT3LG (NP_001292868.1) (Thr28-Gln189) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | Flt3 Ligand |
Alias | Flt3 Ligand Protein, Rat Flt3 Ligand Protein, His Tag |
Size | 50ug, 100ug, 200ug |
Species | Rat |
Host | Insect Cells |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | 20mM Tris, 300mM NaCl, 10% Glycerol, pH7.5 |
Purification | Affinity purification |
Molecular Weight | 19.7 kDa |
Background | FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |