Peptide Library Screening Service

KMD Bioscience is offering our expertise in the construction of phage display peptide libraries as a service for customers' research and development efforts. In the study of protein interactions, there is an urgent need for a high-throughput screening program to meet the needs of a large number of researchers looking for protein or enzyme ligands. 

The phage display platform provided by KMD Bioscience is an ultra-high-throughput ligand screening method. Through this technology platform, up to 1013/ml peptide or antibody clones that have been displayed by phage can be constructed, and the average number of independent clones can be achieved to 109-1010/ml. After multiple rounds of panning, up to 105 effective peptide or antibody sequences can be found, which can provide a solid research foundation for the subsequent search for enzyme substrates, protein ligands and highly specific antibodies research. At the same time, with the affinity screening platform of KMD Bioscience, the affinity ranking of different peptides or antibodies and target proteins can be obtained in a short cycle of time (2-3 days), and even the determination of precise affinity can be completed (affinity determination service). Based on the phage display platform, KMD Bioscience can construct a random 7-peptide library,12-peptide library, cyclic 7-peptide library, etc.

Peptide library construction by phage display has become a major tool of medicine discovery to identify de novo peptide ligands and explore sequence space in proteins. Based on the phage display technology, KMD Bioscience can provide customers with high-quality screening services for a wide range of customized random peptide libraries and premade peptide libraries. (Premade phage display peptide library screening services).

Peptide library construction and screening based on phage display technology has several obvious advantages over compound library peptide library screening. To read more, please click "Similarities and Differences between Phage Display Peptide Library Screening Service and Compound Library Screening Service".

KMD Bioscience is committed to providing high-quality services in peptide library construction, and can customize peptide libraries of various types and applications according to customers' needs. KMD Bioscience's premade peptide libraries and customized peptide library screening platforms provide beneficial tools for scientists. The application areas include: peptide library screening for drug discovery, peptide screening for biomarker discovery, and peptide library screening for vaccine development. Cell receptor targeting peptide screening, peptide drug development customized services, cancer treatment peptide screening, protein interaction peptide screening, cell signaling pathway research peptide screening, functional peptide development services, bioinformatics-assisted peptide library design, specific peptide formulation screening and custom production of synthetic peptide libraries.


Fig. 1 Principle and procedure of peptide library construction


Phage Display Peptide Library Construction Services:


Fig. 2 Phage Display Peptide Library


With rich experiences and well established phage display technology platform, KMD Bioscience can provide a wide range of customized peptide libraries with different lengths and characteristics to meet customers's needs. KMD Bioscience using T7 and M13 phage systems as our featured service.




Nucleotide Sequence Synthesis

Random synthesis of nucleotide sequences of customer specified length

Polymerization and Digestion

Polymerization and digestion of the synthesized DNA sequence

Electroconversion Libraries Preparation

ER2738 host bacteria were prepared, and then E. coli was transformed with the well-constructed recombinant plasmid

Peptide Library Size and Diversity Detection

Detection of peptide library size by colony counting and peptide library diversity by sequencing

Phage Display Peptide Library Generation

By infecting the phage packaging peptide library


Phage Display Peptide Library Screening Services Content:



Service Content


Quality Control of Antigens

Antigen purity testing by SDS-PAGE

3 days

Peptide Library Screening

Positive clones recognizing antigen by 3-4 rounds of screening

2 weeks

Antibody Sequencing

Positive clone sequencing

1 week

Antibody Quality Control

Expression of target antibody in E.coli, followed by quality control by Elisa

1 week


Service Highlights:


-- One-Stop Solutions for your research in immunology, proteomics and medicine discovery.

-- Customized phage display peptide library constructed by KMD Bioscience for high throughput production.

-- Accurate and fast experimental process, saving time and cost.

-- Have professional technical experts to control the screening process accurately.

-- Peptide screening is high specificity and high sensitivity.

-- Widely used in the development of peptide medicines and accurate localization of antigenic determinants.


How to Order?


If you have any questions regarding our services or products, please feel free to contact us by E-mail: or Tel: +86-400-621-6806;