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Catalog Number | KMH1318 |
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Product Name | Recombinant Human LAG3 Protein, His Tag |
Product Description | Recombinant Human LAG3 Protein, His Tag (KMH1318) contains the human LAG3(Leu23-Gly434) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | LAG3 |
Uniprot ID | P18627 |
Alias | CD223, lymphocyte activating 3 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 45.32 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |