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Recombinant Human CD223/LAG3 Protein, His Tag

Product Information
Catalog Number KMH385
Product Name Recombinant Human CD223/LAG3 Protein, His Tag
Product Description Recombinant Human CD223/LAG3 Protein, His Tag (KMH385) contains the human LAG3(Met1-Leu450) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name LAG3
Uniprot ID P18627
Alias CD223, lymphocyte activating 3
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 49.61 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer Supplied as solution form in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 7.5, 150 mM NaCl.
Purification Affinity Purification
Background Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.