KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | MA1555 |
|---|---|
| Product Name | Mouse Anti Human CD3/CD3E Monoclonal Antibody |
| Clonity | Monoclonal |
| Alias | CD3e molecule, epsilon (CD3-TCR complex), CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE |
| Size | 50ul, 100ul |
| Clone Number | 4H41 |
| Isotype | IgG2b |
| Immunogen | CD3 fusion protein(GenBank Accession Number: BC049847) was immunized with mice and purifed by Protein A. |
| Species | Human |
| Host | Mouse |
| Applications | IF, FC, IHC, WB, ELISA |
| Application Dilution | WB : 1:2000-1:20000 IHC : 1:500-1:10000 IF : 1:200-1:800 |
| Application Notes | Positive WB detected in jurkat cells; Positive IHC detected in:human tonsillitis tissue and human colon tissue. |
| Buffer | Supplied in PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification | Protein A |
| Background | CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). |
| Storage | Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
