KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | MA1556 |
|---|---|
| Product Name | Mouse Anti Human CD3(OKT3) Monoclonal Antibody |
| Clonity | Monoclonal |
| Alias | CD3e molecule, epsilon (CD3-TCR complex), CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE |
| Size | 50ul, 100ul |
| Clone Number | OKT3 |
| Isotype | IgG2a |
| Species | Human |
| Host | Mouse |
| Applications | FC |
| Application Notes | Positive FC detected in:human PBMCs |
| Buffer | Supplied in PBS with 0.09% sodium azide, pH 7.2. |
| Purification | Affinity purification |
| Background | CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). |
| Storage | Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
Technical Support：[email protected]
