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Catalog Number | KMH518 |
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Product Name | Recombinant Human 4-1BBL/TNFSF9 Protein, His Tag |
Product Description | Recombinant Human 4-1BBL/TNFSF9 Protein, His Tag (KMH518) contains the human TNFSF9(Ala50-Glu254) was fused with the N-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | TNFSF9 |
Uniprot ID | P41273 |
Alias | CD137L, TNLG5A, 4 1BB L, TNF superfamily member 9 |
Protein Family | Immune checkpoint |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 22.64 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS, pH7.5 |
Purification | Affinity Purification |
Background | CD137 is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), 4-1BB and induced by lymphocyte activation (ILA). The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |