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Mouse TNFSF9 Protein, hFc Tag

Product Information
Catalog Number KMP3831
Product Name Mouse TNFSF9 Protein, hFc Tag
Product Description The Mouse TNFSF9 Protein(KMP3831) is produced in HEK293 Cells. A DNA sequence encoding the Mouse TNFSF9 (NP_033430.1) (Arg104-Glu309) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name TNFSF9
Alias TNFSF9 Protein, Mouse TNFSF9 Protein, hFc Tag
Size 50ug, 100ug, 200ug
Species Mouse
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Molecular Weight 51.41 kDa
Background 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.