KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+86-022-82164980
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
| Catalog Number | KMP3697 |
|---|---|
| Product Name | Cynomolgus TNFSF9 Protein, hFc Tag |
| Product Description | The Cynomolgus TNFSF9 Protein(KMP3697) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus TNFSF9 (XP_015296398.1) (Arg68-Glu251) is expressed with the Fc region of human IgG1 at the N-terminus. The purified protein is biotinylated in vitro. |
| Molecular Name | TNFSF9 |
| Alias | TNFSF9 Protein, Cynomolgus TNFSF9 Protein, hFc Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Cynomolgus |
| Host | HEK293 Cells |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Molecular Weight | 47.8 kDa |
| Background | 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：[email protected]
Hot Line： +86-022-82164980
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