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Human TNFSF9 Protein, Avi Tag, Fc Tag

Product Information
Catalog Number KMP3271
Product Name Human TNFSF9 Protein, Avi Tag, Fc Tag
Product Description The Human TNFSF9 Protein(KMP3271) is produced in HEK293 Cells. The target gene encoding the human TNFSF9 (NP_003802.1) (Arg71-Glu254) is expressed with a N-terminal Avi tag followed by a Fc region of human IgG1 tag. The purified protein is biotinylated in vitro.
Molecular Name TNFSF9
Alias Human TNFSF9 Protein, Avi Tag, Fc Tag, TNFSF9
Molecular Weight 47.98 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.