KMD Bioscience Co., Ltd.
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Email：info@kmdbioscience.com
| Catalog Number | KMP2404 |
|---|---|
| Product Name | Human HAVCR2 Protein, His Tag |
| Product Description | The Human HAVCR2 Protein(KMP2404) is produced in HEK293 Cells and the target gene encoding Ser22-Arg200 is expressed with a 6His tag at the C-terminus. |
| Molecular Weight | 20.7 kDa |
| Alias | Hepatitis A virus cellular receptor 2, HAVCR2 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purification | Affinity purification |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | 20mM PB, 150mM NaCl, pH7.4 |
| Uniprot | E5RHN3#structure |
| SDS-PAGE |  |
| Background | T-Cell Membrane Protein 3(TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence(aa 1-21), an extracellular region(aa 22-202) with one Ig-like V-type domain, a transmembrane segment(aa 203-223), and a cytoplasmic domain(aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte(Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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Email：info@kmdbioscience.com
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