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Catalog Number | MOP2071 |
---|---|
Product Name | Recombinant Mouse B7-1/Cd80 Protein, Fc Tag |
Product Description | Recombinant Mouse B7-1/Cd80 Protein, Fc Tag (MOP2071) contains the mouse Cd80(Val38-Lys245) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
Molecular Name | Cd80 |
Uniprot ID | Q00609 |
Alias | B71, Ly53, TSA1, Cd28l, Ly 53, MIC17, CD80 antigen |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Mouse |
Host | Mammalian cells |
Molecular Weight | 47.88 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | It is widely accepted that T cells require a signal induced by the engagement of the T cell receptor and a "costimulatory" signal(s) through distinct T cell surface molecules for optimal T cell expansion and activation. Members of the B7 superfamily of counterreceptors were identified by their ability to interact with costimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B7-1 (CD8), B7-2 (CD86), B7-H1 (PD-L1), B7-H2 (B7RP-1), B7-H3 and PD-L2. B7-1 is expressed on activated B cells, activated T cells, mature dendritic cells and macrophages. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |