Anti-idiotype Antibody Development Service

KMD Bioscience is experienced in developing custom anti-idiotypic antibodies (anti-ID Abs). The anti-idiotypic antibodies produced by KMD Bioscience have high specificity and affinity to support your research, like preclinical research, clinical trials and biosimilar development research.


Custom Antibody Production-Anti-Idiotype Antibody Generation Service:


An antibody possesses several complementarity-determining regions (CDRs). Anti-idiotypes are typically raised against the CDR regions (idiotype) of the biosimilar antibody. Therapeutic antibody biosimilars (ADC biosimilar) are usually coupled to drugs using CDR1 or CDR3 domains isolated from the variable regions of antibodies and used as a cancer immunotherapy tool.

KMD Bioscience offers a complete protocol of Anti-idiotype antibody production to meet your individual requirements with our independent Phage Display Platform. Combined with our proprietary and innovative phage display technology and gene synthesis technology, hybridoma cell lines and peripheral blood lymphocyte samples, KMD Bioscience can construct a natural,  semi-synthetic or fully synthetic phage display library for our customers (independent clones ~1013, effective clones ~109-10). Monoclonal antibodies with high antigen specificity and high affinity can be screened from these libraries. PCR technology is used to clone the fragment of screened, high-affinity anti-idiotypic antibody to our phagemid expression system. Our systems allow the high expression of anti-idiotypic antibodies in phage, prokaryotic and mammalian expression systems.




--Antibody Biosimilar Immunogenicity Study

--Preclinical studies of therapeutic antibodies

--Clinical development of anti-drug antibodies

--Controls in Ligand Neutralization and Antibody Blocking Assays

--Antibody biosimilar pharmacokinetics (PK) and pharmacodynamics (PD) study: Used for high-throughput detection of specific antibody biosimilar including free, binding and blood.


Service Highlights:


--Full traceable support system, GMP/GLP level

--High-throughput antibody screening platform

--High specificity and binding affinity

--Full-service integration


How to Order?


If you have any questions regarding our services or products, please feel free to contact us by E-mail: or Tel: +86-400-621-6806