2024-03-15 Hits(328)
5T4 (Gene ID:7162) is a glycoprotein found mainly in embryonic trophoblast cells, also known as trophoblast glycoprotein, oncoprotein 5T4, Wnt activation inhibitory factor 1, WAIF1, TPBG, and M6P1. It is expressed mainly in a variety of trophoblast cells during embryonic developmental stages and in a variety of tumor cells. Encoded by the human 5T4 gene, this protein consists of 420 amino acids with a molecular weight of 46.03 kDa and comprises an extracellular domain, transmembrane region and cytoplasmic tail. Studies have shown that 5T4 effectively impedes both the classical Wnt/β-catenin pathway and the non-classical Wnt signaling pathway. And due to its elevated expression in tumors coupled with low expression levels in normal adult tissues, targeting 5T4 has become a focal point for several anti-cancer drugs in clinical development. It plays an important role in cancer research along with other related fields.
KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality TPBG/5T4 proteins, TPBG/5T4 antibodies and other high-quality target products to research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality TPBG/5T4 related products and promoting the continuous innovation and development in the field of biotechnology.
The featured target TPBG/5T4 protein products launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Size |
Inquiry |
KMP3445 |
Human |
HEK293 Cells |
50ug, 100ug, 200ug |
||
KMP3446 |
Human |
HEK293 Cells |
50ug, 100ug, 200ug |
||
KMP4149 |
Mouse |
HEK293 Cells |
50ug, 100ug, 200ug |
||
KMP4150 |
Mouse |
HEK293 Cells |
50ug, 100ug, 200ug |
The featured target TPBG/5T4 antibody product launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Appliance |
Size |
Inquiry |
PA8412 |
Human |
Rabbit |
WB |
50ul, 100ul |
Other advantageous products from KMD Bioscience: