2024-03-15 Hits(387)
The CD3E gene (Gene ID:916) is a component of the CD3 complex, which consists of CD3E, CD3D and CD3Z (also known as CD3-γ, δ and ζ, respectively). These proteins are associated with the TCR and are essential for the function of T cell . In particular, CD3E acts as the ε-chain within the CD3 complex. CD3E is involved in the development of T cells by being expressed early in T cell precursors and facilitating assembly and surface expression of the TCR complex. Without functional CD3E, normal T cell development is impaired. Furthermore, it is essential for antigen recognition by forming a complex with CD3D and CD3Z to complete the overall structure of the TCR complex. This complex binds to antigenic peptides presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E serves as a target for immunotherapy, particularly in the development of bispecific antibodies (BsAbs) and chimeric antigen receptor (CAR) T-cell therapies. BsAbs conjugated with CD3E and tumor-specific antigens redirect T cells to attack cancer cells, while CAR T cells modified with CD3E-specific receptors exhibit promise for a wide range of applications in cancer therapy.
KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality CD3E proteins, CD3E antibodies and other high-quality target products to research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality CD3E related products and promoting the continuous innovation and development in the field of biotechnology.
The featured target CD3E protein products launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Size |
Inquiry |
KMPH2475 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH2476 |
Human |
HEK293 Cells |
20ug, 50ug |
||
PM193 |
Rhesus |
HEK293 Cells |
20ug, 50ug |
||
PM194 |
Rhesus |
HEK293 Cells |
20ug, 50ug |
||
MOP1967 |
Mouse |
HEK293 Cells |
|
||
KMPH5772 |
Human |
HEK293 Cells |
|
||
MOP1968 |
Mouse |
HEK293 Cells |
|
||
KMPH5777 |
Human |
HEK293 Cells |
|
||
KMPH5780 |
Human |
HEK293 Cells |
20ug, 50ug |
||
MOP1971 |
Mouse |
HEK293 Cells |
20ug, 100ug |
||
PM142 |
Cynomolgus Monkey |
|
|
||
KMPH6059 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH6065 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH6187 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH6231 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH6239 |
Human |
|
|
||
KMPH6241 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMPH6261 |
Human |
|
|
||
KMPH6278 |
Human |
|
|
||
KMPH6282 |
Human |
HEK293 Cells |
20ug, 50ug |
||
KMH152 |
Human |
Mammalian cells |
50ug, 100ug |
||
KMP2811 |
Human |
HEK293 Cells |
50ug, 100ug, 200ug |
||
KMP2812 |
Human |
CHO Cells |
50ug, 100ug, 200ug |
||
KMP3539 |
Human |
HEK293 Cells |
50ug, 100ug, 200ug |
The featured target CD3E antibody products launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Appliance |
Size |
Inquiry |
PA6053 |
Human |
Rabbit |
WB, IHC |
50ul, 100ul |
||
PA6055 |
Human |
Rabbit |
WB, IHC, IF |
50ul, 100ul |
||
PA9777 |
Human |
Rabbit |
WB |
50ul, 100ul |
||
PA11011 |
Human |
Rabbit |
WB, IHC, IP |
50ul, 100ul |
||
MA500 |
Human |
Rabbit |
WB, IHC |
50ul, 100ul |
||
MA736 |
Human |
Rabbit |
WB, ELISA, FC |
50ul, 100ul |
Other advantageous products from KMD Bioscience: