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HAVCR2 Target

2024-03-15 Hits(348)

HAVCR2 (Gene ID:84868), also known as TIM-3 (T-cell immunoglobulin and mucin structural domain-containing protein 3), encodes a cell-surface protein that is expressed predominantly on immune cells. TIM-3 plays a pivotal role in regulating the immune response and has been implicated in a variety of immune-related disorders. Initially discovered as a marker on T-cells, TIM-3 has subsequently been detected on other immune cell types, including dendritic cells and natural killer cells. TIM-3 has gained significant attention due to its role in immune checkpoint signaling in the context of T cell exhaustion and immune tolerance. TIM-3 is an immune checkpoint receptor that plays a key role in the regulation of T cell responses by interacting with its ligands, such as galactose lectin-9 and phosphatidylserine (PtdSer), to transmit inhibitory signals. The upregulation of TIM-3 on T cells is involved in processes that lead to T-cell exhaustion, inhibiting their effector functions. This phenomenon has been implicated in chronic infections (e.g., HIV and hepatitis), cancer, and autoimmune diseases. As a result, TIM-3 has emerged as a target for cancer immunotherapy. Antibodies that block TIM-3 interactions can enhance anti-tumor immune responses by preventing T-cell exhaustion and promoting cytotoxic T-cell activity. TIM-3 has been implicated in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Dysregulation of TIM-3 signaling leads to uncontrolled immune activation.

KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality HAVCR2 protein, HAVCR2 antibody and other high-quality target products for research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality HAVCR2 related products and promoting the continuous innovation and development in the field of biotechnology.

The featured target HAVCR2 protein products launched by KMD Bioscience:

CAT#	Products Name	Specise	Host	Size	Inquiry
KMPH1552	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH1553	Human HAVCR2/TIM3 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
MOP1874	Mouse HAVCR2/TIM3 Protein, Fc Tag	Mouse	HEK293 Cells	50ug, 100ug	Inquiry
MOP1875	Mouse HAVCR2/TIM3 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5907	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5908	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5909	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5910	Human HAVCR2/TIM3 Protein, Strep Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5911	Human HAVCR2/TIM3 Protein, Fc & His Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH5912	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMPH6035	Human HAVCR2/TIM3 Protein, Fc Tag	Human	HEK293 Cells	50ug, 100ug	Inquiry
KMH513	Recombinant Human HAVCR2 Protein, His Tag	Human	Mammalian cells	50ug, 100ug	Inquiry
MOP2174	Recombinant Mouse Havcr2/Tim-3 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	Inquiry
MOP2294	Recombinant Mouse TIM-3/Havcr2 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	Inquiry
KMH1807	Recombinant Human TIM-3/HAVCR2 C-fc Protein, Fc & His Tag	Human	Mammalian cells	50ug, 100ug	Inquiry
MOP2295	Recombinant Mouse TIM-3/Havcr2 C-fc Protein, Fc Tag	Mouse	Mammalian cells	50ug, 100ug	Inquiry
KMH1808	Recombinant Human TIM-3/HAVCR2 Protein, His Tag	Human	Mammalian cells	50ug, 100ug	Inquiry
MOP2296	Recombinant Mouse TIM-3/Havcr2 Protein, His Tag	Mouse	Mammalian cells	50ug, 100ug	Inquiry
KMP2288	Human HAVCR2 Protein, mFc Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2301	Human HAVCR2 Protein, Fc Tag, Avi Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2310	Cynomolgus HAVCR2 Protein, Fc Tag	Cynomolgus	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2336	Mouse HAVCR2 Protein, Fc Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2340	Mouse HAVCR2 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2352	Marmoset HAVCR2 Protein, His Tag	Marmoset	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2354	Mouse HAVCR2 Protein, His Tag	Mouse	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2382	Human HAVCR2 Protein, Fc Tag, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2399	Cynomolgus HAVCR2 Protein, His Tag	Cynomolgus	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP2404	Human HAVCR2 Protein, His Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry

The featured target HAVCR2 antibody products launched by KMD Bioscience:

CAT#	Products Name	Specise	Host	Appliance	Size	Inquiry
PA7062	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IF	50ul, 100ul	Inquiry
PA7063	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	IHC, IF	50ul, 100ul	Inquiry
PA7064	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IHC	50ul, 100ul	Inquiry
PA10794	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB	50ul, 100ul	Inquiry
PA12960	Rabbit Anti-Human HAVCR2 pAb	Human	Rabbit	WB, IHC	50ul, 100ul	Inquiry
PAV1688	Rabbit Anti-HAVR2/HAVCR2 Polyclonal Antibody	WB, ELISA	Rabbit	WB, ELISA	100ul	Inquiry

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HAVCR2 Target