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CD137 (Gene ID:3604) belongs to the tumor necrosis factor (TNF) receptor family and is an inducible co-stimulatory receptor, also known as TNFRSF9, 4-1BB, which is widely expressed on the surface of activated T cells, macrophages, natural killer cells, eosinophils, neutrophils, and mast cells, as well as regulatory T cells, and its expression can be induced by leukocyte activation. The protein encoded by CD137 consists of 255 amino acids with a molecular weight of 27.9 kDa and contains extracellular, intracellular, transmembrane, and signaling peptides, and its intracellular domains are lack enzymatic activity. CD137 binds to its ligand, CD137L to provide potent co-stimulatory signals that regulate T-cell-mediated immune responses including activation, proliferation, or apoptosis. Moreover, the signals sent by CD137 can stimulate the proliferation of natural killer cells and T cells while exerting anti-tumor effects. Therefore, CD137 has the ability of anti-tumor lymphocyte activation and pro-inflammatory polarization, and is a star target in the field of tumor immunotherapy, which plays an important role in the research of tumor and other related fields.
KMD Bioscience is an innovative biotechnology company dedicated to providing high-quality TNFRSF9/CD137 proteins, antibodies, and other target products to research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality TNFRSF9/CD137 related products and promoting the continuous innovation and development in the field of biotechnology.
The featured target TNFRSF9/CD137 protein products launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Size |
Inquiry |
KMPH1151 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH1152 |
Human |
HEK293 Cells |
100ug, 200ug |
||
PCA188 |
Canine |
HEK293 Cells |
100ug, 200ug |
||
PCA190 |
Canine |
HEK293 Cells |
100ug, 200ug |
||
PM346 |
Rhesus |
HEK293 Cells |
100ug, 200ug |
||
PM347 |
Rhesus |
HEK293 Cells |
100ug, 200ug |
||
KMPH5791 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5792 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5793 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5794 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5795 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5796 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5797 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMPH5798 |
Human |
HEK293 Cells |
100ug, 200ug |
||
KMH313 |
Human |
Mammalian cells |
50ug, 100ug |
||
KMH614 |
Human |
Mammalian cells |
50ug, 100ug |
The featured target TNFRSF9/CD137 antibody product launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Appliance |
Size |
Inquiry |
PA12670 |
Human |
Rabbit |
WB, IHC |
50ul, 100ul |
Other advantageous products from KMD Bioscience: