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Galactose lectin-9 (LGALS9) (Gene ID:3965) is a gene that encodes the protein Galactose lectin-9, a member of the Galectin family known for its specific binding ability. Galactose lectin-9 is involved in a variety of physiological processes, including immune regulation and inflammation. Galactose lectin-9 was initially identified as a protein that binds to beta-galactoside and is expressed in a variety of tissues, including the liver, spleen, and lymph nodes. It has since been recognized for its immunomodulatory function and its role in regulating the immune response. Galactose lectin-9 plays a crucial role in immunomodulation and is involved in the regulation of both innate and adaptive immune responses. It selectively interacts with its receptor TIM-3 (T-cell immunoglobulin and mucin structural domain-containing protein 3), which is expressed predominantly on immune cells, including T-cells, NK-cells, and dendritic cells. The relationship between Galactose lectin-9 and interaction between Galactose lectin-9 and TIM-3 on T cells leads to inhibition of T cell responses. This interaction induces T cell apoptosis (cell death) and exhaustion, suppresses effector T cell activity, and contributes to immune tolerance. Galactose lectin-9 has anti-inflammatory properties; it inhibits the production of pro-inflammatory cytokines and promotes the production of anti-inflammatory cytokines, which helps to reduce excessive inflammation.
KMD Bioscience is an innovative biotechnology company, dedicated to providing high-quality LGALS9 protein, LGALS9 antibody and other high-quality target products for research institutions, universities and companies. Adhering to the principle of customer first, KMD Bioscience is committed to providing the best quality LGALS9 related products and promoting the continuous innovation and development in the field of biotechnology.
The featured target LGALS9 protein products launched by KMD Bioscience:
CAT# |
Products Name |
Specise |
Host |
Size |
Inquiry |
Immune checkpoint |
Recombinant Human Galectin-9/LGALS9 Protein, His Tag |
Human |
E. coli |
50μg, 100μg |
|
KMPH5922 |
Human |
HEK293 Cells |
|
||
KMH521 |
Human |
E. coli |
50ug, 100ug |
||
KMH610 |
Human |
Mammalian cells |
50ug, 100ug |
Other advantageous products from KMD Bioscience: